High Prices For Orphan Drugs Strain Families And Insurers

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Before Luke Whitbeck began taking a $300,000-a-year drug, the 2-year-old's health was inexplicably failing.

A pale boy with enormous eyes, Luke frequently ran high fevers, tired easily and was skinny all over, except his belly stuck out like a bowling ball.

"What does your medicine do for you?" Luke's mother, Meg, asked after his weekly drug treatment recently.

Donald Trump loves superlatives: words like "biggest," "best," and "greatest" pepper many of his statements, whether at a microphone or on Twitter. But a recent poll lends him another, less attractive superlative: the lowest favorability rating of any incoming president in at least 40 years.

Donald Trump and Barack Obama don't agree on much, but when Trump takes the oath of office to succeed Obama on Friday, there will be one small but symbolic similarity on display. Trump will place his hand on the Bible that President Lincoln used at his first inauguration, the same one President Obama used at both of his swearing in ceremonies.

In a presidential campaign marked by harsh rhetoric, Donald Trump directed some of his strongest words toward China. He called the Chinese government a currency manipulator, threatened to impose tariffs on goods imported from one of America's leading trade partners and repeatedly vowed to get tough on China.

Russian President Vladimir Putin said Tuesday that the Obama administration is attempting to "undermine the legitimacy" of President-elect Donald Trump.

U.S. intelligence agencies have concluded that the Russian government, at the direction of Putin, hacked several U.S. targets as part of an "influence campaign" to shape the outcome of the election.

The long arm of the pharmaceutical industry continues to pervade practically every area of medicine, reaching those who write guidelines that shape doctors' practices, patient advocacy organizations, letter writers to the Centers for Disease Control and Prevention and even oncologists on Twitter, according to a series of papers on money and influence published Tuesday in JAMA Internal Medicine.

Britain's prime minister said Tuesday that the United Kingdom will walk away from the European Union's single market and unified court system, making a sharp break with its largest trading partner.

In a speech delivered about six months after voters passed a referendum requiring Britain to leave the EU, Prime Minister Theresa May laid out a plan for what that split would look like, emphasizing limits on migration into the country.

Several times a month, you can find a doctor in the aisles of Ralph's market in Huntington Beach, Calif., wearing a white coat and helping people learn about food. On one recent day, this doctor was Daniel Nadeau, wandering the cereal aisle with Allison Scott, giving her some ideas on how to feed kids who studiously avoid anything that tastes healthy.

"Have you thought about trying smoothies in the morning?" he asks her. "The frozen blueberries and raspberries are a little cheaper, and berries are really good for the brain."

In a major speech at the World Economic Forum in Davos, Switzerland, Chinese President Xi Jinping positioned himself as a defender of globalization and free trade.

The abortion rate in the United States fell to its lowest level since the historic Roe v. Wade Supreme Court decision legalized abortion nationwide, a new report finds.

The report by the Guttmacher Institute, a research group that supports legalized abortion, puts the rate at 14.6 abortions per 1,000 women of childbearing age (ages 15-44) in 2014. That's the lowest recorded rate since the Roe decision in 1973. The abortion rate has been declining for decades — down from a peak of 29.3 in 1980 and 1981.

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